Node DIP
Core-Team: Wolfgang Wadsak, Oliver Langer
Speaker: Wolfgang Wadsak
The node for the Development of Imaging Probes (DIP) aims to develop and optimize imaging probes (PET, SPECT, MR, ...) and to establish a “one-stop-shop“ for researchers dealing with these molecular probes.
The DIP node offers specific expertise in the following areas:
- Medicinal chemistry & radiochemistry for (pre-)clinical use
- Preclinical and (radio-)pharmacological testing
- Quantitative imaging aspects
- Mass spectrometry applications
The main research areas of this node are based on a close interaction with the respective research clusters and centers at the Medical University of Vienna as well as its departments and core facilities. At present, the DIP node focuses on the following topics:
- Molecular Imaging Biomarkers in Oncology (e.g. angiogenesis, hypoxia, proliferation) and Cardiovascular Disease (e.g. atherosclerosis)
- Neuroimaging (e.g. central receptors, transporters and enzymes in neurotransmission; blood-brain-barrier penetration and efflux transporters; neurodegenerative diseases)
- Pharmacokinetic imaging (radiolabelling of drugs and drug candidates)
- Combined Biomarkers for in-vivo hybrid techniques (e.g. PET/MR)
- Theranostic agents for the direct translation from diagnostic imaging to therapeutic applications
The DIP node closely cooperates with the other nodes within this cluster, in particular with Preclinical Imaging, Quantitative Clinical Imaging and Image Guided Therapy & Theranostics.
QUO VADIS – Node Vision
Multimodal one-stop shop for imaging probes
- State-of-the-art radiochemistry
- Nanostructures for multifold modalities
- Theranostic probes
- Labeling of large molecules (peptides, antibodies)
- Contrast agents
Partners and Teams
Main Topic: Oncology and Cardiovascular Disease
- Alexander Haug & Markus Hartenbach, Universitätsklinik für Radiologie und Nuklearmedizin
- Leopold Schmetterer, Zentrum für Medizinische Physik und Biomedizinische Technik
- Gerald Stübiger, Zentrum für Physiologie und Pharmakologie
- Beatrix Wulkersdorfer, Universitätsklinik für Klinische Pharmakologie
- Gülen Yerlikaya, Universitätsklinik für Frauenheilkunde
Main Topic: Neuroimaging
- Roland Beisteiner, Universitätsklinik für Neurologie
- Rupert Lanzenberger, Universitätsklinik für Psychiatrie und Psychotherapie
- Markus Mitterhauser, Universitätsklinik für Radiologie und Nuklearmedizin
- Christian Pifl, Abteilung für Molekulare Neurowissenschaften
- Daniela Prayer, Universitätsklinik für Radiologie und Nuklearmedizin
- Matthäus Willeit, Universitätsklinik für Psychiatrie und Psychotherapie
- Markus Zeitlinger, Universitätsklinik für Klinische Pharmakologie
Main Topic: Theranostic Probes
- Dietmar Georg, Universitätsklinik für Strahlentherapie
- Marcus Hacker, Universitätsklinik für Radiologie und Nuklearmedizin
Main Topic: Multimodal Probes
- Markus Mitterhauser, Universitätsklinik für Radiologie und Nuklearmedizin
- Siegfried Trattnig, Universitätsklinik für Radiologie und Nuklearmedizin
- Wolfgang Birkfellner, Zentrum für Medizinische Physik und Biomedizinische Technik