Node PI
Core-Team: Markus Mitterhauser, Thomas Helbich
Speaker: Markus Mitterhauser
The Preclinical Imaging (PI) node bridges the gap between experimental strategies and clinical application of innovative novel imaging biomarkers and/or methods.
The main research areas of this node are based on a close interaction with the respective departments of MedUni Vienna. At present, the PI node focuses on imaging in:
- Oncology (angiogenesis, hypoxia, proliferation, metabolism, cell death)
- Cardiovascular research (atherosclerosis, vulnerable plaques, myocardial perfusion/ischaemia)
- Neurology (Psychiatry, Neuro-Oncology, Epilepsy, Alzheimer’s disease, Parkinson’s disease)
- Musculoskeletal research (arthritis, pain, inflammation)
The activities of the PI node are closely related to the Preclinical Imaging Laboratory (PIL). The PIL focuses on the application of sophisticated imaging techniques in experimental systems and small experimental animals. The panel of available techniques include micro-MR, micro-CT, micro-SPECT, micro-PET, micro-ultrasound and various optical imaging procedures (bioluminescence, fluorescence) as well as options for the combination of these methods (hybrid technologies). Complimentary, for precise induction of tissue and organ alterations, a dedicated small animal irradiation device is available. The PIL is closely and intensely cooperating with the Department of Biomedical Imaging and Image guided Therapy in order to instantly exploit the preclinical research into clinical applications.
QUO VADIS – Node Vision
- Multimodal one-stop shop for Preclinical Imaging
- Translational research
- Development of state of art biomarkers for Precision Medicine
- Development of disease models
- Development of humanized models
Partners and Teams
Main Topic: Oncology
- Zsuzsanna Bago-Horvath, Klinisches Institut für Pathologie
- Walter Berger, Institut für Krebsforschung
- Alexander Dohnal
- Thomas Helbich, Universitätsklinik für Radiologie und Nuklearmedizin
- Reinhard Kirnbauer, Universitätsklinik für Dermatologie
- Manfred Lehner
Main Topic: Psychiatry and Neurology
- Roland Beisteiner, Universitätsklinik für Neurologie
- Rupert Lanzenberger, Universitätsklinik für Psychiatrie und Psychotherapie
- Daniela Prayer, Veronika Schöpf, Universitätsklinik für Radiologie und Nuklearmedizin
- Jürgen Sandkühler, Abteilung für Neurophysiologie
- Markus Zeitlinger, Oliver Langer, Universitätsklinik für Klinische Pharmakologie
Main Topic: Osteology/Immunology
- Alexander Dohnal
- Silvia Hayer, Universitätsklinik für Innere Medizin III
- Renate Kain, Institut für Klinische Pathologie
- Sylvia Knapp, Universitätsklinik für Innere Medizin I
- Erika Jensen-Jarolim, Institut für Pathophysiologie und Allergieforschung
- Hugo Partsch, Universitätsklinik für Dermatologie
- Peter Pietschmann, Institut für Pathophysiologie und Allergieforschung
Main Topic: Cardiovascular Diseases
- Christoph Binder, Klinische Abteilung für Medizinisch-chemische Labordiagnostik
- Marcus Hacker, Universitätsklinik für Radiologie und Nuklearmedizin
- Andreas Janata, Universitätsklinik für Notfallmedizin
- Martin Krssak, Universitätsklinik für Innere Medizin III
- Irene Lang, Universitätsklinik für Innere Medizin II
- Johannes Schmid, Institut für Gefäßbiologie und Thromboseforschung